Mechanism of therapeutic efficacy of Wobenzym in the treatment of toxic
hepatitis
Korpan M.I., Korpan N.N., Tschekman I.S., Fialka V.
National Medical University, Kiev
Dopovidi Nacionalnoi akademii nauk Ukrainy, 1997, 9, 184-187
The experimental study was held to clear up a mechanism of the treatment effect of the drug Wobenzym in rats with toxic hepatitis, which was provoked by carbon tetrachloride. Wobenzym in doses of 5, 20, and 100 mg/kg manifests a normalizing influence on the activity of alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, and on the amounts of common and connected bilirubins in blood plasma of rats in the case of toxic hepatitis.
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